The Channeling Hope Foundation is excited to host the 2nd International NALCN Channel & Related Diseases Conference (NALCN 2025) in San Antonio, Texas, USA, from October 10-12, 2025. The conference brings together international scientists and clinicians to present and discuss ground-breaking research on the NALCN ion channel and related diseases, leaders to identify current research gaps, opportunities and priorities to develop the first therapies for these diseases, and families to build our community and start the first natural history study.